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Cancer: Gastric (Stomach) Cancer

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Total 20166 results found since Jan 2013.

A Positive HIV Test Shattered His Dreams of Serving in the U.S. Army. Now He ’ s Suing
One cold winter morning in 2008, 8-year-old Isaiah Wilkins decided to try on his mother’s National Guard uniform, something he always wanted to do. She was away at training in Texas, but she kept an extra uniform at home in Temple, Georgia. Young Isaiah climbed up to the attic of his parents’ single-story house and spotted the blue 30-gallon bin where his mother stored her military clothes. He unclicked the clips on the sides, lifted the lid, and rummaged through the neatly organized items. After carefully shuffling through a few patches and her combat boots, he spotted her uniform. [time-brightcove not-tgx=...
Source: TIME: Health - December 1, 2022 Category: Consumer Health News Authors: Jordan Gonsalves Tags: Uncategorized HIV/AIDS Military Source Type: news

Boosted protease inhibitor monotherapy versus boosted protease inhibitor plus lamivudine dual therapy as second-line maintenance treatment for HIV-1-infected patients in sub-Saharan Africa (ANRS12 286/MOBIDIP): a multicentre, randomised, parallel, open-label, superiority trial
This study is registered with ClinicalTrials.gov, number NCT01905059. Findings Between March 5, 2014, and Jan 26, 2015, 265 participants were assigned to receive monotherapy (133) or boosted protease inhibitor plus lamivudine (132). At week 48, an independent data safety monitoring board reviewed data, and advised discontinuation of the monotherapy group because the number of failures had exceeded the expected 20%; therefore results here are for week 48. At this point, treatment failure occurred in four (3·0%; 95% CI 0·8–7·6) of 132 participants on dual therapy and 33 (24·8%; 17·7–33·0) of 133 participants on mon...
Source: The Lancet HIV - May 29, 2017 Category: Infectious Diseases Source Type: research

Co-formulated bictegravir, emtricitabine, and tenofovir alafenamide versus dolutegravir with emtricitabine and tenofovir alafenamide for initial treatment of HIV-1 infection: week 96 results from a randomised, double-blind, multicentre, phase 3, non-inferiority trial
This study was registered with ClinicalTrials.gov, number NCT02607956.FindingsBetween Nov 13, 2015, and July 14, 2016, we screened 742 individuals, of whom 657 were enrolled. 327 participants were assigned to the bictegravir group and 330 to the dolutegravir group. Of these, 320 in the bictegravir group and 325 in the dolutegravir group received at least one dose of study drug. At week 96, HIV-1 RNA less than 50 copies per mL was achieved by 269 (84%) of 320 participants in the bictegravir group and 281 (86%) of 325 in the dolutegravir group (difference −2·3%, 95% CI −7·9 to 3·2), demonstrating non-inferiority of th...
Source: The Lancet HIV - May 6, 2019 Category: Infectious Diseases Source Type: research

Woman diagnoses her own ovarian cancer with Google search
Sadie Rance turns to internet search engine for answers after being told stomach pains and constipation were due to Irritable Bowel Syndrome
Source: Telegraph Health - February 6, 2015 Category: Consumer Health News Tags: search ovarian Irritable Bowel Syndrome Sadie Rance diagnosed Cancer Google Source Type: news

Arsenic: a Culpable Element and a Possible Menace for HIV/AIDS Patients
This article addresses the immunotoxicity of arsenic and exacerbations caused by it, along with the neurotoxicity, particularly in HIV patients residing near the Gangetic belt.PMID:35128593 | DOI:10.1007/s12011-022-03097-7
Source: Biological Trace Element Research - February 7, 2022 Category: Biology Authors: Akanksha Singh P Ramalingam Sameer Dhingra V Ravichandiran Krishna Murti Source Type: research

Unmasked immune reconstitution inflammatory syndrome towards B-cell non-Hodgkin lymphoma during treatment of esophageal actinomycosis in a patient with advanced HIV: a case report
CONCLUSION: Esophageal actinomycosis in people living with HIV is very rare. We suggest HIV-associated immunosuppression is not enough to allow for actinomycosis to develop, and masked underlying entities should be sought. The existence of such entities in people living with HIV should raise awareness of the possibility of unmasked immune reconstitution inflammatory syndrome once treatment has started.PMID:37452343 | DOI:10.1186/s12981-023-00526-y
Source: Cell Research - July 14, 2023 Category: Cytology Authors: Elsa K Vargas-Garcia Augusto R Fernandez-Aristi Gonzalo Cornejo-Venegas Juan Jos é Montenegro-Idrogo Juan Chirinos-Vega Alfredo Chiappe-Gonzalez Source Type: research

Medicine: the appliance of science
A cure for HIV? A new approach to obesity? Tailor-made therapies for cancer? Medical science surges aheadMore than once last year, researchers described leaps in medical science that were so breathtaking, and held so much potential for patients, that they immediately joined the list of fields to watch in the year ahead. In most cases, the work was, and is, at an early stage and its future success far from certain. Such is the nature of science. Most of today's breakthroughs will be tomorrow's failures. But some may go down in history for transforming how medicine is done.Often, medical science surges ahead when different a...
Source: Guardian Unlimited Science - January 1, 2013 Category: Science Authors: Ian Sample Tags: The Guardian Genetics Biology Medical research Microbiology Society Features Cancer Aids and HIV Chemistry Biochemistry and molecular biology Science Source Type: news

Risk and Predictors of Esophageal and Stomach Cancers in HIV-Infected Veterans: A Matched Cohort Study
Conclusion: HIV-infected individuals with low CD4 count are at highest risk for ESCC, but HIV infection was not independently associated with EAC or gastric cancer after adjusting for confounders.
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - June 13, 2019 Category: Infectious Diseases Tags: Epidemiology Source Type: research

Brief Report: The Influence of HIV Status on the Burden and Clinical Manifestations of Gastrointestinal Pathogens in Yangon, Myanmar.
Abstract The impact of HIV infection on the burden of gastrointestinal pathogens in Myanmar is poorly defined. Stools of 103 HIV-infected and 105 HIV-uninfected adult outpatients at a tertiary referral hospital in Yangon were examined microscopically. Stool antigen tests for Helicobacter pylori infection were positive in 63/103 (61%) HIV-infected and 61/105 (58%) HIV-uninfected patients (P = 0.65). Soil-transmitted helminth infections were much less common, occurring in 9/103 (9%) HIV-infected and 13/103 (13%) HIV-uninfected patients (P = 0.50). One HIV-uninfected patient had Giardia duodenalis, but there were no ...
Source: Am J Trop Med Hyg - February 23, 2020 Category: Infectious Diseases Authors: Pa Pa Aung W, Myint NPST, Zaw TT, Cooper DA, Aung NM, Kyi MM, Lwin MM, Hanson J Tags: Am J Trop Med Hyg Source Type: research

HIV and cancer registry linkage identifies a substantial burden of cancers in persons with HIV in India
Abstract: We utilized computerized record-linkage methods to link HIV and cancer databases with limited unique identifiers in Pune, India, to determine feasibility of linkage and obtain preliminary estimates of cancer risk in persons living with HIV (PLHIV) as compared with the general population. Records of 32,575 PLHIV were linked to 31,754 Pune Cancer Registry records (1996–2008) using a probabilistic-matching algorithm. Cancer risk was estimated by calculating standardized incidence ratios (SIRs) in the early (4–27 months after HIV registration), late (28–60 months), and overall (4–60 months) incidence periods...
Source: Medicine - September 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Detection and quantification of EBV, HHV-6 and CMV DNA in the gastrointestinal tract of HIV-positive patients
Abstract Human herpes viruses (HHVs) have been frequently detected in the gastrointestinal (GI) tract and may contribute to the development of gastric cancer. In the present study, the detection rate and viral load of Epstein Barr virus (EBV), HHV-6 and Cytomegalovirus (CMV) were assessed in the GI tract of human immunodeficiency virus (HIV) positive patients and of uninfected patients. The analysis revealed a significantly higher detection rate of EBV and HHV-6 in HIV-infected individuals than in uninfected subjects (88.5 vs 63 %; p = 0.03). Moreover, EBV DNA load was significantly higher in the stomach of HIV...
Source: Infection - October 18, 2014 Category: Infectious Diseases Source Type: research

Molecular profiling of gastric cancer in a population with high HIV prevalence reveals a shift to MLH1 loss but not the EBV subtype
Human immunodeficiency virus infection is associated active Epstein ‐Barr virus (EBV) infection. We found that this does not necessarily translate into an increased proportion of EBV‐associated gastric cancer. We also found a much higher proportion of microsatellite unstable tumors than that reported elsewhere. These findings provide good preliminary data that c ould be helpful in understanding not only gastric carcinogenesis but probably avenues for new therapies as well. AbstractThe human immunodeficiency virus (HIV) pandemic heavily affects sub ‐Saharan Africa. It is associated with persistently active Epstein‐B...
Source: Cancer Medicine - March 24, 2020 Category: Cancer & Oncology Authors: Violet Kayamba, Julia Butt, Tim Waterboer, Ellen Besa, Naheed Choudhry, Anglin Hamasuku, Peter Julius, Douglas C. Heimburger, Masharip Atadzhanov, Paul Kelly Tags: ORIGINAL RESEARCH Source Type: research